# FSC 239-How are the allele frequency tables

FRSC3000H ASSIGNMENT #3DUE: Tuesday Mar 15th, 2016 in the Forensic Science Assignment Dropbox before 3pm.NOTES: Show all work legibly, all equations, and all units for full marks (25 marks total).Point form answers are preferred, be concise and to the point, or marks may be deducted!1. How are the allele frequency tables (such as the ones in your textbook) calculated? When creating allelefrequency tables what are two factors you might need to consider? (3 marks)2. Why are the statistics used to calculate RMP different if there is a relation involved? (2 marks)3. What is a random match probability and why is it used? (2 marks)4. Assume the database that was used to generate Table 1 consists of 36 individuals. Using this information,what is (show equations and calculations) the probability that two individuals have the same profile of163/165; 145/145; C/D if (and no, allele D is not a typo):a) they are unrelated, but from a smaller demographic, explain use of equation (4 marks)b) there could be a parent-offspring relationship possible, explain use of equation (4 marks)c) there could be a sibling relationship possible, explain use of equation (4 marks)Table 1:Locus A161 Freq (locus A)0.2 Locus B141 Freq (locus B)0.01 Locus CA Freq (locus C)0.5 163165 0.40.4 143145 0.350.64 BC 0.40.1 Page 1 of 2 5. Given the following electropherogram, and the information in Table 2, what are the individual profiles ofthe major and minor contributors to this profile and their gender? Mathematically justify your answer andshow your work (6 marks)Table 2. RFUs per locusAmelogeninD3TH01D13D16D2 106 = 1050014 = 32006 = 53008 = 381110 = 80416 = 2998 D3S1358 TH01 112 =150015 = 10009 = 140011 = 461111 = 89817 = 2881 D13S317 D16S539 16 = 30009.3 = 400012 = 99912 = 264520 = 1012 17 = 900 13 = 259925 = 945 D2S1338 Page 2 of 2